Answer
Ancient country in SW Asia, between the upper Tigris & Euphrates rivers: a part of modern Iraq. Loosely. the entire region between these rivers, extending to the Persian Gulf
The prehistoric terms "meso," which meant between or in the middle, and "potamos," which meant river, were combined to form the word "mesopotamia." Modern-day Iraq, Kuwait, Turkey, and Syria are located in the region's lush valleys between the Tigris and Euphrates rivers.